Single oral pill could be cure for malaria
The new pill compound uses natural red pigment, which is taken from a soil bacteria. According to the results, this compound has cured malaria in just one oral dose in the study’s animal models. In addition, the pill also appears to defend the body against drug resistant strains of malaria.
The discovery began when a research found an old paper, which was published in the 1970s, which suggested that the pigment may treat malaria.
“Why didn’t anyone follow-up on it,” Kevin Reynolds, the principal investigator, said. “Perhaps they didn’t have the know-how or technology to make the structural changes necessary to make it more effective.”
The fact that the treatment is available in the form of a pill and not a vaccine or injection that requires specific transportation needs means that this treatment could be more accessible to more people around the world.
“What’s unique about our research is the potential to create a one-pill cure for malaria,” Reynolds said. “That’s huge because it’s not an injection that needs to be kept refrigerated and you wouldn’t need multiple doses.”
Further details are available in the Journal of Medicinal Chemistry.