Innovative sequencing successfully detects resistant pathogens

Innovative sequencing successfully detects resistant pathogens
Innovative sequencing successfully detects resistant pathogens | Courtesy of
Kalorama Information, a healthcare market researcher, recently reported that next-generation sequencing may allow researchers to bypass the negative qualities of molecular testing, placing sequencing in an important role for clinical tests.

Using NGS within lab operations is will become more crucial with time as antimicrobial resistance and pathogen typing become increasingly important. As strains evolve and mutate, molecular tests do not change quickly enough to keep pace; alternatively, sequencing is a flexible testing method for detecting antimicrobial resistance and pathogens.

Kalorama reports that standard approaches lack the adaptability to keep pace with the rapidly changing viruses around the world. Even though probe and primer selection involved in molecular assays has been well-developed, antimicrobial-resistant and virulent strains and clones can easily escape detection of traditional molecular primers and probes.

"Specificity is molecular diagnostics' major strength, but is also a weakness when assay development isn't caught up with microbial adaptation," Emil Salazar, analyst for Kalorama Information, said. "NGS can overcome this limitation with the flexibility to detect any number of genetic variants."

Further details about market information, next-generation sequencing, healthcare-acquired infections and similar trends are available thanks to Kolorama Information. Current reports include Health Associated Infection (HAI) Control Markets as well as Next Generation Sequencing (NGS) Markets 2015.

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