TUESDAY, JUNE 19, 2018

Researchers discover new drug formulations to fight antibiotic-resistant superbugs

Researchers from the Agency for Science, Technology and Research's Institute of Chemical Engineering Sciences (ICES) and the National University Hospital (NUH) recently discovered a way to treat antibiotic-resistant bacteria and respiratory system infections.

The researchers believe the new drug formulations aimed at combating superbugs will allow doctors to prescribe smaller and more effective doses to patients, ScienceDaily reports.

The three superbug-fighting drug formulations are each made up of three different antibiotics. The antibiotics complement each other by fighting bacteria differently while potentially having the ability to be interchanged, preventing bacteria from developing resistance to drugs, according to ScienceDaily.

The formulations, which can be inhaled directly, are the result of a partnership between the Agency for Science, Technology and Research and NUH that began in 2010. The collaboration is currently looking to move into clinical trials to test the efficacy and stability of the formulations.

"I am delighted that the work stems from the results of our expertise in inhaled novel formulations," Keith Carpenter, the executive director of ICES, said, ScienceDaily reports. "This is an excellent example of how our collaboration with the local medical community is helping to translate our research from bench to bedside, and further developing innovative therapies for patients."

Researchers from ICES also recently developed four drug formulations of muco-actives and antibiotics that proved effective in laboratory testing in treating respiratory syndrome infections or bacteria-linked pulmonary diseases.