GlaxoSmithKline makes vaccine executive changes

by Ted Purlain on March 12, 2010

Glaxosmithkline

GlaxoSmithKline

LONDON — British pharmaceutical company GlaxoSmithKline PLC on March 12 announced two changes in the executive lineup of its vaccines business.

Emergent BioSolutions’ CEO recognized as outstanding international business leader

by Tina Redlup on March 12, 2010

El-hibri_fuad

Fuad El-Hibri

ROCKVILLE, Md. — The World Trade Center Institute announced March 11 that Emergent BioSolutions Inc.’s chairman and CEO has been named as one of Maryland’s outstanding international business leade

Battelle, IBM, Merck join university in plan for vaccine factory

by Pat Dulnier on March 11, 2010

Upmc

An ambitious plan to build a vaccine factory in the Pittsburgh area is gaining momentum with the announcement March 11 of three new partners in the University of Pittsburgh Medical Center project, the Pittsburgh Business Times reported.

'Painless' vaccine needle invented in Japan

by Tina Redlup on March 4, 2010

Flu_vaccine

Kanji Takada, a professor of pharmacokinetics, has developed a round vaccine "chip" measuring 1.5 centimeters in diameter that contains as many as 300 micro needles.

Flightless mosquitoes may curb dengue, researchers say

by Rita Uplend on February 24, 2010

Malaria_mosquito

WASHINGTON — Genetically altered mosquitoes that cannot fly may help slow the spread of dengue fever and could be a harmless alternative to chemical insecticides, U.S. and British scientists said Feb. 22.

Researchers' group slams decision to cancel HIV-vaccination facility

by Ted Purlain on February 24, 2010

Hiv

HIV

The head of an association that represents Canada's HIV researchers is criticizing a federal government decision to scrap plans for an $83.5 million facility that would manufacture potential vaccines.

Indiana fund invests in vaccine research

by Rita Uplend on February 22, 2010

Vaccine

INDIANAPOLIS — BioCrossroads' Indiana Seed Fund has invested in Bioscience Vaccines Inc. to accelerate the development of biologic materials, which may boost the effectiveness of a wide range of life-saving vaccines.

Study shows how viruses altered evolution

by Tina Redlup on February 19, 2010

Poli-di-milano

Politecnico di Milano

LONDON — Italian scientists said Feb. 19 that they had found evidence of how viruses helped change the course of human evolution and said their discovery could help in the design of better drugs and vaccines.

Nabi Biopharmaceuticals completes PentaStaph milestone

by Rita Uplend on February 8, 2010

Nicvax

NicVAX

ROCKVILLE, Md. — Nabi Biopharmaceuticals announced Feb. 8 that it has completed the manufacture and transfer of specified materials associated with the sale of the PentaStaph vaccine candidate to GlaxoSmithKline Biologicals.

Novavax, Rovi end flu vaccine development plan

by Tina Redlup on February 8, 2010

Novavax-vlp-vaccine

Novavax's viruslike particle vaccines

TEL AVIV, Israel — Novavax Inc. announced Feb. 8 that it ended talks aimed at a collaboration with Rovi Pharmaceuticals of Madrid to develop Novavax's viruslike particle vaccines against influenza in Spain.

President’s budget boosts funds for tropical diseases

by Ted Purlain on February 4, 2010

Flu_vaccine

WASHINGTON — President Barack Obama's budget proposes a unique new initiative — battling some tropical diseases not just to improve health but as a national security strategy, Reuters reported Feb. 2.

NanoBio Awarded Key Patent Covering Vaccine and Anti-Infective Product Platforms

by Pat Dulnier on February 3, 2010

Flu_vaccine

Flu Vaccine

NanoBio Corp. announced Feb. 2 that a sixth U.S. patent covering its novel nanoemulsion technology has been awarded. The patent encompasses composition of matter claims for the company’s lead anti-infective and vaccine product candidates.

Some viruses use fats to penetrate a cell

by Tina Redlup on February 3, 2010

Sv40

SV40

SV40 viruses use an amazing means of communication, in order to be able to penetrate into a cell: fats, whose structure must fit like a key in a lock, ScienceDaily reported Jan. 29.

Cadila Pharmaceuticals’ H1N1 vaccine faces technical hurdle

by Rita Uplend on February 2, 2010

India-flag

NEW DELHI — Cadila Pharmaceuticals’ plans to manufacture H1N1 flu vaccines has hit a roadblock as the drug regulator has expressed concerns over the technology to be used.

Immune response better with skin scratch vaccination, study says

by Paul Tinder on January 18, 2010

Smallpox-virus-ns

Smallpox

Giving a vaccine through a scratch on the skin triggers a stronger immune response than injected vaccines and requires 100 times less vaccine to prompt an immune response, HealthDay News reported Jan. 17.

Emergent BioSolutions says CFO to join board of MdBio Foundation

by Paul Tinder on January 13, 2010

Elsey_don

R. Don Elsey

ROCKVILLE, Md. — Emergent BioSolutions Inc. announced Jan. 11 that its chief financial officer and senior vice president of finance and administration has joined the board of directors of the MdBio Foundation.

Swedish research might point to stomach cancer vaccine

by Tina Redlup on December 31, 2009

Stomach-cancer

Stomach Cancer

GOTHENBURG, Sweden — New research at Sahlgrenska Academy might be an important step toward creating a vaccine against ulcers and stomach cancer, The Local reported Dec. 30.

Extremely drug-resistant TB found in U.S.; weaker form spreads globally

by Rita Uplend on December 29, 2009

Tuberculosis

TB

Public health officials are concerned about the implications of the first U.S. case of extremely drug-resistant tuberculosis, diagnosed in a 19-year-old Peruvian who is visiting here to study English, Homeland Security Today reported Dec. 29.

Vical reports benefits of DNA technology platform with vaccine for H1N1 flu

by Paul Tinder on December 29, 2009

Dna

DNA

SAN DIEGO — Vical Inc. announced the publication of data documenting the successful pilot lot production and initiation of animal immunogenicity testing of a Vaxfectin-adjuvanted DNA vaccine for H1N1 influenza.

Sanofi-aventis to acquire Chattem, broaden consumer health care bas

by Paul Tinder on December 22, 2009

Sanofi-aventis_logo

Sanofi-aventis

Sanofi-aventis and Chattem Inc. announced Dec. 21 that they have entered into an agreement under which sanofi-aventis is to acquire 100 percent of the outstanding shares of Chattem in a cash tender offer for approximately $1.9 billion.

Fast method for preparing flu vaccine developed

by Ted Purlain on December 16, 2009

Cox-manon

Manon Cox

Someday, effective vaccines might be produced two to four times the speed of vaccines manufactured in fertilized chicken eggs, according to a researcher in the Netherlands.

Human trial for spoon-fed vaccines to begin

by Ted Purlain on December 10, 2009

Helicobacter

Helicobacter

Human trials are soon to begin on an Australian-pioneered technique that could revolutionize the way we vaccinate — by replacing the syringe with the spoon, the Australian Associated Press reported Dec. 8.

Health experts say more funds needed for TB tests, drugs, vaccines

by Tina Redlup on December 10, 2009

Tuberculosis

Tuberculosis

CANCUN, Mexico — Health experts called for more research funding to develop better diagnostic tests, vaccines and drugs for tuberculosis, which killed 1.8 million people around the world last year.

Scientists reveal malaria parasites' tactics for outwitting our immune systems

by Daniel Purt on December 3, 2009

Malaria

Malaria

Malaria parasites are able to disguise themselves to avoid the host's immune system, according to research funded by the Wellcome Trust and published Dec. 1 in the journal Proceedings of the National Academy of Sciences.

Aspirin, Tylenol may decrease effectiveness of vaccines, researchers say

by Pat Dulnier on December 2, 2009

Pbb_protein_cox1_image

COX-1

With flu season in full swing and the threat of H1N1 looming, demand for vaccines is at an all-time high. However, researchers suggest that over-the-counter drugs may lessen their effect, ScienceDaily reported Dec. 2.

New report shows 97 medicines and vaccines in development for HIV/AIDS

by Pat Dulnier on December 2, 2009

Fauci_anthony

Anthony Fauci

WASHINGTON, D.C. — America’s pharmaceutical research and biotechnology companies are testing 97 medicines and vaccines to treat or prevent HIV/AIDS and related conditions.

Unknown disease affects more than 100 people, causes 3 deaths in Congo

by Pat Dulnier on November 28, 2009

Who

BRAZZAVILLE, Republic of Congo — An unknown epidemic caused three deaths and affected more than 100 people in the last few days in the Republic of Congo.

GlaxoSmithKline says trial shows Pandemrix has strong response

by Pat Dulnier on November 24, 2009

Stephenne

Jean Stephenne

LONDON -- GlaxoSmithKline announced Nov. 23 that more than 40 million doses of its adjuvanted pandemic H1N1 vaccine have been distributed to countries globally for use in government-initiated vaccination programs.

Next-generation flu vaccine plant to open in North Carolina

by Rita Uplend on November 24, 2009

Flu_vaccine

Flu Vaccine

WASHINGTON -- Novartis will officially open the first next-generation flu vaccine plant in the United States on Nov. 24, but it will be years before it makes its first vaccine.

H1N1 mutations detected in Norway

by Ted Purlain on November 24, 2009

Who

GENEVA -- The Norwegian Institute of Public Health has informed the World Health Organization of a mutation detected in three H1N1 viruses.

Md. governor praises Emergent BioSolutions

by Daniel Purt on November 20, 2009

Omalley_martin

Gov. Martin O’Malley

ANAPOLIS, Md. — Maryland Gov. Martin O’Malley praised Emergent BioSolutions for its upcoming expansion in East Baltimore during his online economic update released Nov. 19.

Fighting tuberculosis should be priority, Fauci says

by Tina Redlup on November 20, 2009

Fauci_anthony

Dr. Anthony Fauci

Dr. Anthony Fauci wrote this commentary, posted Nov. 17, for msnbc.com. He is director of the National Institute of Allergy and Infectious Diseases in Bethesda, Md.

BusinessWeek calls Genocea Biosciences 1 of world’s most intriguing startups

by Ted Purlain on November 19, 2009

Bakali_staph

Staph Leavenworth Bakali

Genocea Biosciences, a vaccine discovery and development company, announced Nov. 16 that it was named one of BusinessWeek’s “World’s Most Intriguing Startups” for 2009.

FDA wants panel to probe Pfizer vaccine efficacy

by Pat Dulnier on November 18, 2009

Emilio_emini

Dr. Emilio Emini

WASHINGTON — Pfizer Inc's next-generation Prevnar vaccine missed some of the main goals in a study testing its ability to protect against bacteria that cause ear infections, pneumonia and other diseases.

HIV vaccine failure probably caused by virus used, new research says

by Pat Dulnier on November 18, 2009

Hiv

HIV

The recent failure of an HIV vaccine was probably caused by the immune system reacting to the virus “shell” used to transmit the therapy around the body, according to research published Nov. 16 in the Proceedings of the National Academy of Sciences.

Scientists create NICE solution to pneumonia vaccine testing problems

by Paul Tinder on November 18, 2009

Hwang_jeeseong

Jeeseong Hwang

Medical clinics could benefit from new software created at the National Institute of Standards and Technology, where a team of scientists has found a way to improve the efficiency of a pneumonia vaccine testing method.

Progress toward Alzheimer's vaccine, says Israeli researcher

by Pat Dulnier on November 17, 2009

Monsonego_alon

Alon Monsonego

JERUSALEM — An Israeli researcher working on a vaccine to combat Alzheimer's disease said Nov. 9 that he had made important progress following tests on gene-altered laboratory mice.

Kansas University receives $6 million contract for vaccine research

by Rita Uplend on November 17, 2009

Nih

Kansas University has been awarded a five-year, $6.85 million research contract with the goal of boosting the effectiveness and safety of vaccines that treat infectious diseases.

GSK, Nabi announce agreement for vaccine for nicotine addiction

by Pat Dulnier on November 17, 2009

Stephenne

Jean Stephenne

LONDON and ROCKVILLE, Md. — GlaxoSmithKline Biologicals and Nabi Biopharmaceuticals have announced an exclusive worldwide option and licensing agreement for a vaccine for the treatment of nicotine addiction.

Emergent BioSolutions acquires manufacturing facility from MdBio

by Pat Dulnier on November 16, 2009

El-hibri_fuad

Fuad El-Hibri

ROCKVILLE, Md. — Emergent BioSolutions Inc. announced that it has completed the acquisition of a 55,000-square-foot manufacturing facility from MdBio Foundation and the land on which the facility stands from the city of Baltimore.

GSK: Trial of 2 vaccines shows promise to treat H1N1, seasonal flu at same time

by Paul Tinder on November 12, 2009

Stephenne

Jean Stéphenne

LONDON — GlaxoSmithKline announced Nov. 9 the results from the clinical trial assessing Pandemrix, GSK’s adjuvanted H1N1 influenza vaccine, administered at the same time as the annual seasonal influenza vaccine, Fluarix.

Study of key HIV antibodies could lead to new vaccine design

by Paul Tinder on November 11, 2009

Alam

S. Munir Alam

A study of how the most robust antibodies work to block HIV as it seeks entry into healthy cells has revealed a new direction for researchers hoping to design an effective vaccine, ScienceDaily reported Nov. 10.

Rare Ebola-like virus poses new threat to U.S. troops in Afghanistan

by Tina Redlup on November 11, 2009

Ebola

Ebola

KANDAHAR, Afghanistan — U.S. military officials sent a medical team to a remote outpost in southern Afghanistan this week to take blood samples from members of an Army unit after a soldier in the unit died from an Ebola-like virus.

Vaccinated moms less likely to have small or premature babies

by Mary J. Lewis on October 31, 2009

William_schaffner

Dr. William Schaffner

PHILADELPHIA — Pregnant women who get the flu vaccine are less likely to have babies who are premature or are small for their gestational age, according to two new studies.

Emergent BioSolutions’ chief financial officer named SmartCFO of the Year

by Daniel Purt on June 15, 2009

Elsey_don

Don Elsey

ROCKVILLE, Md. — Emergent BioSolutions Inc. announced June 15, 2009, that Don Elsey, its chief financial officer and senior vice president of finance and administration, has been named 2009 SmartCFO of the Year by SmartCEO Magazine.

Emergent BioSolutions initiates Phase II trial of oral typhoid vaccine candidate

by Ted Purlain on June 5, 2008

Abdun_nabi

Daniel J. Abdun-Nabi

ROCKVILLE, MD. —Emergent BioSolutions Inc. announced that dosing of patients has begun in a U.S. Phase II clinical trial of the company’s single-dose oral typhoid vaccine candidate.

Former DHHS secretary joins board of directors of Emergent BioSolutions

by Tina Redlup on June 21, 2006

Dept-hhs

GAITHERSBURG, Md. — Emergent BioSolutions Inc. announced June 21, 2006, that a former secretary of the U.S. Department of Health and Human Services has been named to its board of directors.

Emergent BioSolutions’ typhoid vaccine achieves positive results in clinical study

by Ted Purlain on August 30, 2005

Typhoid_salmonella_

GAITHERSBURG, Md. — Emergent BioSolutions announced positive results from a Phase II clinical study evaluating a simplified dosing regimen for the company’s next-generation single-dose oral typhoid vaccine.