Study finds new antimalarial treatment effective for children
The report, released in PLOS Medicine, was conducted by San Francisco General Hospital and the Makerere University College of Health Sciences in Kampala, Uganda, ScienceDaily reports.
The study, which enrolled 393 infants from Tororo, Uganda, used monthly treatments of dihydroartemisinin-piperaquine (DP) and two other treatment regimes in a randomized, controlled trial. The results showed that DP had a protective efficacy rate of 58 percent, according to ScienceDaily.
"The excellent efficacy of DP for the treatment of malaria in multiple countries and for chemoprevention in our high transmission area suggest that this regimen will offer benefit in many regions in need of improved control measures," the authors of the study said, ScienceDaily reports.
The authors also said that future studies are needed to better study the preventative efficacy of DP in other areas and maintain surveillance to identify drug-resistant parasites.
There were no significant adverse effects in the patients as a result of the DP treatments in the year after they stopped receiving them. The findings suggested that DP is a safe and effective method for treating malaria in infants, according to ScienceDaily.