Baby given overdose of TB vaccine

by Ted Purlain on March 9, 2010

Vaccine

LONDON — An investigation is under way after a newborn baby was given 10 times the normal dose of a tuberculosis vaccine at a hospital in North Lincolnshire, England.

1 in 5 at-risk babies in U.S. doesn't get hepatitis B vaccine

by Ted Purlain on March 8, 2010

Hepb

Hepatits B

About one in five babies born to mothers with hepatitis B aren't getting treatments that have been shown to prevent the infection in newborns, a study whose findings were released online March 8 in advance of the April print issue of Pediatrics.

U.S. H1N1 vaccine campaign challenging, speakers say

by Ted Purlain on March 6, 2010

H1n1

H1N1

WASHINGTON — First, people were clamoring for H1N1 vaccines, but there were not enough to go around. By the time vaccines were available in any quantity, most of the public had lost interest.

85 million children to be immunized across 19 countries

by Ted Purlain on March 4, 2010

Polio

Polio

More than 85 million children under five years old will be immunized against polio in 19 countries across West and Central Africa in a massive cooperation aimed at stopping a year-long polio epidemic the World Health Organization announced.

Findings confirm H1N1 flu's toll on pregnant women

by Ted Purlain on March 4, 2010

H1n1

H1N1

NEW YORK — New research from Australia confirms that the HIN1 flu hits pregnant women particularly hard — especially if they have asthma, obesity or diabetes.

Coalition for Vaccine Safety calls for congressional hearings

by Ted Purlain on March 3, 2010

Cdc

A new coalition is calling for hearings to investigate HHS, the Centers for Disease Control and Prevention and other government agencies for what it describes as a failure to fully address issues of vaccine safety.

Egg allergy no bar to flu shot, researchers say

by Ted Purlain on March 2, 2010

Flu_vaccine

NEW ORLEANS — Most children with egg protein allergies who received influenza vaccinations had no adverse reactions, researchers said at the annual meeting of American Academy of Allergy, Asthma & Immunology, according to MedPage Today.

WHO official sees promise from India cholera vaccine

by Ted Purlain on March 1, 2010

Cholera

Cholera

GENEVA — Because deadly cholera infections are still on the rise, producing oral cholera vaccines in poor countries could help boost the immunity of those most vulnerable to the water-borne disease, a World Health Organization official said March 1.

NIH, FDA announce initiative to fast-track innovations to public

by Ted Purlain on February 27, 2010

Nih

The U.S. Food and Drug Administration and the National Institutes of Health unveiled an initiative designed to accelerate the process from scientific breakthrough to the availability of new, innovative medical therapies for patients.

Older women not likely to benefit from cervical cancer vaccine

by Ted Purlain on February 25, 2010

Hpv

HPV

Women older than 40 are unlikely to get much benefit from the vaccine for the virus that causes cervical cancer, a new study reports.

2009 H1N1 flu strain will be in next season flu vaccine

by Ted Purlain on February 25, 2010

Cdc

The 2009 H1N1 flu virus, which has sickened millions and killed at least 15,000 people worldwide, will be included in the United States’ next seasonal flu vaccine when it becomes available in the fall, government health experts decided.

Researchers' group slams decision to cancel HIV-vaccination facility

by Ted Purlain on February 24, 2010

Hiv

HIV

The head of an association that represents Canada's HIV researchers is criticizing a federal government decision to scrap plans for an $83.5 million facility that would manufacture potential vaccines.

UNICEF backs measles vaccination campaign in Bangladesh

by Ted Purlain on February 22, 2010

Measles

Measles

More than 20 million Bangladeshi children will be vaccinated against measles over the next two weeks as part of a campaign backed by UNICEF to try to eradicate the deadly disease in the South Asian nation, the UN News Service reported Feb. 15.

Virxsys researches using AIDS to fight AIDS

by Ted Purlain on February 19, 2010

Hiv

HIV

WASHINGTON — A company using genetically engineered versions of the AIDS virus says its unusual approach is getting some results, both for treating and perhaps as a vaccine against HIV.

MMR vaccine doctor Andrew Wakefield quits autism centre

by Ted Purlain on February 18, 2010

Wakefield-andrew

Andrew Wakefield

Andrew Wakefield, the British doctor whose research triggered a health scare over the measles, mumps and rubella vaccine, has resigned from the autism center he founded in Texas, The Guardian reported Feb. 18.

Senegal confirms H1N1 outbreak

by Ted Purlain on February 16, 2010

H1n1

H1N1

DAKAR, Senegal — Modou Diagne Fada, Senegal’s minister of health and preventive medicine, confirmed that the country had been hit by the epidemic H1N1 influenza, AfricaNews reported Feb. 9

Measles continues to spread in Zimbabwe

by Ted Purlain on February 15, 2010

Measles

Measles

HARARE, Zimbabwe — Measles continues to spread in Zimbabwe despite intensified efforts by the government and its partners to contain the outbreak, which has affected more than 1,200 people since October, The Herald reported Feb. 10.

Vaccine not fail-safe in ongoing mumps outbreak

by Ted Purlain on February 12, 2010

Mumps

Mumps

In a recent mumps outbreak occurring in the eastern United States, even some of those who were vaccinated against the infectious illness got sick, health officials report according to HealthDay News.

Preteen vaccine campaign has a Native American spokesperson

by Ted Purlain on February 11, 2010

Vaccine

The Centers for Disease Control and Prevention is partnering with the Indian Health Service to launch a campaign informing American Indian and Alaska Native parents about the importance of a preteen medical check-up and preteen vaccines.

Global Tamiflu-resistant H1N1 cases reach 225

by Ted Purlain on February 10, 2010

Who

World Health Organization

The World Health Organization reported that 225 cases of H1N1 flu with resistance to oseltamivir (Tamiflu) have been found worldwide, and resistant viruses have spread from person to person in several clusters but have not spilled into the community.

H1N1 flu still out there, officials caution

by Ted Purlain on February 9, 2010

Cdc

WASHINGTON — H1N1 flu is still circulating around the world and still killing people, although it is on the decline everywhere, global health officials said Feb. 5.

Bivalent polio vaccine introduced in Delhi, U.P.

by Ted Purlain on February 8, 2010

Polio

Polio

NEW DELHI — Union Health and Family Welfare Minister Ghulam Nabi Azad on Feb. 7 launched the bivalent oral vaccine against polio in Delhi and Uttar Pradesh states to mark India’s national immunization day, The Hindu reported.

25 percent of Americans get H1N1 vaccine, CDC director says

by Ted Purlain on February 5, 2010

Cdc

More than 75 million Americans, or close to 25 percent of the population, have been vaccinated against the pandemic H1N1 virus, the director of the Centers for Disease Control and Prevention estimated Feb. 4.

President’s budget boosts funds for tropical diseases

by Ted Purlain on February 4, 2010

Flu_vaccine

WASHINGTON — President Barack Obama's budget proposes a unique new initiative — battling some tropical diseases not just to improve health but as a national security strategy, Reuters reported Feb. 2.

Researchers say dengue fever cases surge in Central, Latin America

by Ted Purlain on February 4, 2010

Dengue-mosquito

SANTIAGO, Chile — Dengue cases in Central and Latin America have increased almost five-fold in incidence in the last 30 years, researchers have found.

Trial nicotine vaccine may help prevent smoking addiction, relapse

by Ted Purlain on February 3, 2010

Nicvax

NicVAX

Oregon Health & Science University is participating in a Phase III clinical trial to determine whether a new investigational smoking cessation aid called NicVAX is safe, effective and capable of stimulating an immune response, the school announced Feb. 3.

The Lancet retracts study linking autism to vaccine

by Ted Purlain on February 2, 2010

Mmr

LONDON — The Lancet medical journal formally retracted a paper that caused a 12-year international battle over links between the three-in-one childhood measles, mumps and rubella vaccine and autism.

Gates: $10 billion vaccine program could save 8.7 million lives

by Ted Purlain on February 1, 2010

Gates-bill

Bill Gates

DAVOS, Switzerland — Bill and Melinda Gates announced plans Jan. 29 to invest $10 billion in the fight against a number of illnesses including AIDS and said the record donation could save nearly nine million lives.

Canada gives WHO 5 million doses of H1N1 vaccine

by Ted Purlain on January 27, 2010

H1n1

H1N1

TORONTO — Canada has revealed what it will do with a portion of the country's large H1N1 vaccine surplus, announcing Jan. 28 that it is giving 5 million doses to the World Health Organization.

Vical to present vaccine development programs

by Ted Purlain on January 26, 2010

Phacilitate-2010

Vical Inc. announced that it would present an overview of its DNA vaccine and adjuvant technologies and an update on its clinical-stage vaccine development programs at the Phacilitate Vaccine Forum in Washington.

Novavax to present at Phacilitate's North American Vaccine Forum

by Ted Purlain on January 26, 2010

Phacilitate-2010

ROCKVILLE, Md.--Two officials from Novavax Inc. announced Jan. 25 that they will be presenting at Phacilitate's eighth annual Vaccine Forum Washington 2010.

Nigerian officials say H1N1 flu vaccine ‘not available’

by Ted Purlain on January 22, 2010

H1n1

H1N1

Two weeks after A/H1N1 killed a 38-year-old woman and eight others subsequently tested positive, Lagos state government disclosed that Nigeria currently "has no vaccine to treat the flu virus in stock," AllAfrica.com reported Jan. 20

New measles outbreak in Zimbabwe

by Ted Purlain on January 20, 2010

Measles

Measles

BIKITA, Zimbabwe — Ten infants have died of measles in the past five days, health authorities here told Radio VOP on Jan. 20.

Swiss warn on flu vaccine with autoimmune disease

by Ted Purlain on January 19, 2010

Flu_vaccine

ZURICH — Switzerland's medical regulator recommended that patients with serious autoimmune diseases should not use an H1N1 flu vaccine from Novartis, saying there were no studies assessing the inoculation in that segment of the population.

GlaxoSmithKline’s quarterly sales of H1N1 vaccine lower than forecast

by Ted Purlain on January 18, 2010

Who

World Health Organization

LONDON — GlaxoSmithKline confirmed Jan. 15 that approximately 130 million doses of its pandemic H1N1 adjuvanted vaccine were shipped to governments in the fourth quarter of 2009.

Merck submits Gardasil data for women 27 to 45

by Ted Purlain on January 15, 2010

Fda-logo

NEW YORK — Merck & Co on Jan. 13 said it had provided U.S. regulators with new information needed for approval to market its Gardasil cervical cancer vaccine to women between the ages of 27 to 45, Reuters reported.

Vaccine drive set as yellow fever strikes in Guinea

by Ted Purlain on January 12, 2010

Yellow_fever

Yellow Fever

DAKAR, Senegal — Guinean health officials plan this month to vaccinate more than 250,000 people in the northeast against yellow fever after one confirmed and several suspected cases emerged in the region.

U.S. officials wary of another wave of H1N1 flu

by Ted Purlain on January 12, 2010

H1n1

H1N1

Citing mistakes made in the 1957 flu pandemic, federal officials on Jan. 7 urged hesitant Americans to get vaccinated now against H1N1 flu to prevent any possibility of another wave of illness and deaths.

Leukemia vaccine being developed

by Ted Purlain on January 4, 2010

Leukemia

Leukemia

LONDON — A vaccine for leukemia is about to be tested on human patients for the first time, in a breakthrough that could offer hope to thousands of people, the Telegraph reported Jan. 4.

Short-term school closings doesn’t block flu outbreaks, researchers say

by Ted Purlain on December 31, 2009

Cdc

Short-term school closings are not an effective way to block the spread of influenza viruses, and may even be counterproductive, Pennsylvania researchers have found.

TB figures continue to increase in the United Kingdom

by Ted Purlain on December 29, 2009

Tuberculosis

TB

The number of people developing tuberculosis continues to increase despite earlier signs of stabilizing, according to a report released Dec. 2 by the United Kingdom’s Health Protection Agency.

Measles kill 22 in Zimbabwe

by Ted Purlain on December 28, 2009

Measles

Measles

Measles primarily affects children younger than 5 and can lead to blindness, inflammation of the middle ear, brain damage and death.

Canadian officials discuss fate of surplus H1N1 vaccine doses

by Ted Purlain on December 26, 2009

Who

World Health Organization

TORONTO — Canada is in discussions with pandemic vaccine maker GlaxoSmithKline and with the World Health Organization about what to do with the country's expected surplus of H1N1 vaccine, the head of the Public Health Agency of Canada said Dec. 9.

Flu pandemic may change U.S. flu approach forever, officials say

by Ted Purlain on December 24, 2009

Cdc

WASHINGTON — The swine flu pandemic may have changed the U.S. approach to handling influenza forever, and for the better, U.S. officials said Dec. 17 according to Reuters.

Former CDC director named president of Merck Vaccines

by Ted Purlain on December 22, 2009

Gerberding-julie

Dr. Julie Gerberding

WHITEHOUSE STATION, N.J. — Merck & Co. Inc. announced that a former director of the Centers for Disease Control and Prevention has been named president of Merck Vaccines, effective Jan.

H1N1 deaths worldwide top 10,000, WHO says

by Ted Purlain on December 18, 2009

Who

World Health Organization

There have been more than 10,000 swine flu deaths worldwide since April, the World Health Organization said Dec. 18.

Study shows adjuvant boosts response to H1N1 vaccine

by Ted Purlain on December 17, 2009

Mf59

MF59

Novartis's pandemic H1N1 flu vaccine generated stronger immune responses when it was combined with an adjuvant than when used alone, though both formulations yielded good results, according to a report published by the New England Journal of Medicine.

Researchers work on vaccine to improve immune system in newborns

by Ted Purlain on December 16, 2009

Newborn

As soon as babies are born, they are susceptible to diseases and infections, such as jaundice and E. coli. For up to a month, their immune systems aren't adequately developed to fight diseases.

Fast method for preparing flu vaccine developed

by Ted Purlain on December 15, 2009

Cox-manon

Manon Cox

Someday, effective vaccines might be produced two to four times the speed of vaccines manufactured in fertilized chicken eggs, according to a researcher in the Netherlands.

Stem cells can be engineered to kill HIV, scientists show

by Ted Purlain on December 14, 2009

Hiv

HIV

Researchers have for the first time demonstrated that human blood stem cells can be engineered into cells that can target and kill HIV-infected cells — a process that potentially could be used against a range of chronic viral diseases.

Human trial for spoon-fed vaccines to begin

by Ted Purlain on December 10, 2009

Helicobacter

Helicobacter

Human trials are soon to begin on an Australian-pioneered technique that could revolutionize the way we vaccinate — by replacing the syringe with the spoon, the Australian Associated Press reported Dec. 8.

N.Y. autopsies show 2009 H1N1 influenza virus damages entire airway

by Ted Purlain on December 9, 2009

H1n1

H1N1

In fatal cases of 2009 H1N1 influenza, the virus can damage cells throughout the respiratory airway, much like the viruses that caused the 1918 and 1957 influenza pandemics.

Skepticism on H1N1 flu’s danger limits European vaccine demand

by Ted Purlain on December 8, 2009

Flu_vaccine

H1N1 Vaccine

Fewer Europeans are getting pandemic flu vaccine than typically get seasonal flu shots, as safety concerns and lower-than-expected death rates have damped demand, Bloomberg reported Dec. 8.

Union takes hospital to arbitration over workers’ refusal to get vaccination

by Ted Purlain on December 7, 2009

Child-hosp-phil

Children's Hospital of Philadelphia

PHILADELPHIA — A union is taking the Children's Hospital of Philadelphia to arbitration because five people who refused to get the seasonal flu vaccine said they were fired.

Make cancer vaccine more affordable, Nobel laureate says

by Ted Purlain on December 2, 2009

Harald-zur-hausen_420

Harald zur Hausen

CALCUTTA, India — Cervical cancer vaccines should cost less to be more effective in lowering the death rate caused by the disease a Nobel laureate said, according to a report in The Times of India on Dec. 3.

WHO prequalifies GlaxoSmithKline’s H1N1 pandemic vaccine

by Ted Purlain on December 2, 2009

Who

LONDON — GlaxoSmithKline announced Dec. 1 that the World Health Organization has awarded prequalification for global use of Arepanrix, its adjuvanted H1N1 pandemic vaccine manufactured in Canada.

Children under 10 need 2 doses of H1N1 vaccine, parents reminded

by Ted Purlain on November 30, 2009

Flu_vaccine

H1N1 Vaccine

COLUMBUS, Ohio – The Ohio Department of Health reminded parents and health care providers Nov. 30 that children younger than 10 should receive two doses of H1N1 flu vaccine in order to achieve optimal protection against pandemic flu.

WHO donates 9 million flu shots to Philippines, 14 million to Nigeria

by Ted Purlain on November 27, 2009

MANILA, Philippines — The World Health Organization promised on Nov. 26 to donate 9 million H1N1 flu shots to the Philippines, and assured the country the vaccines were safe, Reuters reported.

Baxter hopes to build U.S. cell-based vaccine manufacturing plant

by Ted Purlain on November 27, 2009

Baxter-international

DEERFIELD, Ill. — Baxter International Inc. says it is looking into building a cell-based vaccine manufacturing plant in the U.S. to produce seasonal and pandemic flu vaccines, the Chicago Tribune reported Nov. 26

New HIV infections reduced by 17 percent over 8 years

by Ted Purlain on November 26, 2009

Who

GENEVA and SHANGHAI — According to new data in the 2009 AIDS epidemic update, new HIV infections have been reduced by 17 percent over the past eight years, the World Health Organization and United Nations Program on HIV/AIDS announced Nov. 24.

H1N1 mutations detected in Norway

by Ted Purlain on November 24, 2009

Who

GENEVA -- The Norwegian Institute of Public Health has informed the World Health Organization of a mutation detected in three H1N1 viruses.

BusinessWeek calls Genocea Biosciences 1 of world’s most intriguing startups

by Ted Purlain on November 19, 2009

Bakali_staph

Staph Leavenworth Bakali

Genocea Biosciences, a vaccine discovery and development company, announced Nov. 16 that it was named one of BusinessWeek’s “World’s Most Intriguing Startups” for 2009.

Canada shrugs off cost of flu vaccination campaign

by Ted Purlain on November 16, 2009

H1n1

H1N1

OTTAWA — Canada's top medical official defended the national H1N1 vaccination campaign on Nov. 12, and said the costs of doing nothing would be far higher than the money spent immunizing millions of people.

Malaria outbreak in Virginia

by Ted Purlain on November 13, 2009

Malaria

Malaria

ATLANTA -- There were ten cases of malaria reported across the United States during the week ending October 10th, four of which occurred in Virginia.

Vical official says DNA vaccine technology addresses challenges of emerging diseases

by Ted Purlain on November 13, 2009

Vical

GALVESTON, Texas — Vical Inc. reported Nov. 10 that it has a strong rationale advocating the use of DNA vaccine technology for emerging and/or pandemic infectious diseases.

National polio vaccinations under way in Chad

by Ted Purlain on November 11, 2009

Polio

Polio

GOZ BEIDA, Chad —A three-day nationwide polio vaccination campaign began Oct. 30 throughout Chad, including in the east where according to the World Health Organization the rate of routine immunizations is among the weakest nationwide, IRIN news reported.

Russia's health minister warns media against spreading flu panic

by Ted Purlain on November 10, 2009

Golikova_tatyana

Tatyana Golikova

MOSCOW — Russia's health minister warned the media against spreading panic over a swine and seasonal flu outbreak and said the situation was under control.

Novartis receives regulatory approval in Germany for Celtura

by Ted Purlain on November 9, 2009

Oswald_andrin

Andrin Oswald

BASEL, Switzerland — Novartis announced Nov. 5 that it received approval from the German regulatory authorities for its adjuvanted cell culture-based Influenza H1N1 2009 monovalent vaccine, Celtura.

Deadly tropical disease hits south Sudan

by Ted Purlain on November 6, 2009

Msf

MALAKAL, Sudan — Southern Sudan is facing a "serious outbreak" of the deadly kala azar tropical disease, the aid agency Medecins Sans Frontieres, also known as Doctors Without Borders, warned Friday.

How long does hepatitis B vaccine protection last?

by Ted Purlain on November 4, 2009

Dr_mcmahon

Dr. Brian J. McMahon

The hepatitis B vaccine – given to protect against infection by a virus that can cause severe liver damage and cancer — may protect for more than two decades, according to a new study.

2nd dose of H1N1 vaccine elicits better response in youngest children

by Ted Purlain on November 2, 2009

Niaidlogo

NIAID

The National Institute of Allergy and Infectious Diseases announced interim trial results showing that children 9 years old and younger have improved immune response when given a second 15-microgram dose of 2009 H1N1 influenza vaccine.

IDSA strengthens mandatory immunization policy

by Ted Purlain on October 30, 2009

Dr

Dr. Anne Gershon

To better protect patients and health care workers, the Infectious Diseases Society of America recently strengthened its policy on mandatory immunization of workers. The strengthened statement applies to both seasonal influenza and 2009 H1N1 influenza.

New York suspends flu shot mandate for health care employees

by Ted Purlain on October 27, 2009

Gov_paterson

Gov. Paterson

The mandatory influenza immunization requirement for New York health care workers was suspended Oct. 22 so that the limited vaccine supplies can be used for populations most at risk of serious illness and death.

Novavax launches study of H1N1 VLP Flu Vaccine in Mexico

by Ted Purlain on October 26, 2009

Rahul_singhvi

Rahul Singhvi

Novavax Inc. announced Oct. 23 that it has initiated a two-stage clinical study of its virus-like-particle (VLP) H1N1 influenza vaccine in Mexico in collaboration with Avimex Laboratories and GE Healthcare.

U.S., Mexican and Canadian officials to collaborate against H1N1

by Ted Purlain on October 9, 2009

320_cp24_swine_030509

MEXICO CITY — Department of Homeland Security Secretary Jane Holl Lute joined her Mexican and Canadian counterparts in Mexico City to discuss continued collaboration to confront the spread of global H1N1 flu.

Cholera vaccine seen safe, effective in India study

by Ted Purlain on September 20, 2009

A cholera vaccine has proved to be safe and effective in young children in a part of India where the disease is endemic, a new study in The Lancet says.

Emergent BioSolutions announces start of anthrax treatment trial

by Ted Purlain on March 17, 2009

Niaid_logo

National Institute of Allergy and Infectious Diseases

ROCKVILLE, Md. — Emergent BioSolutions Inc. announced March 17, 2009, that the Phase I/II clinical trial for its anthrax immune globulin (AIG) therapeutic candidate has commenced with the initial treatment given to the first subject.

U.S. to purchase 14.5 million more doses of BioThrax

by Ted Purlain on October 1, 2008

Biothrax

BioThrax

Emergent BioSolutions Inc. announced that it has signed a contract with the U.S. Department of Health and Human Services to supply an additional 14.5 million doses of BioThrax for inclusion in the Strategic National Stockpile.

Emergent BioSolutions gets $24 million to develop anthrax monoclonal antibody

by Ted Purlain on September 3, 2008

Anthrax2

Anthrax

ROCKVILLE, Md. — Emergent BioSolutions Inc. announced Sept. 3, 2008, that it has received a contract from the Department of Health and Human Services for about $24.3 million to further develop of its anthrax monoclonal antibody AVP-21D9.

NIAID awards 2 grants to Emergent BioSolutions for vaccine development

by Ted Purlain on July 24, 2008

Niaid_logo

National Institute of Allergy and Infectious Disease

Emergent BioSolutions Inc. announced that it has secured two grants totaling more than $4.5 million from the NIAID to fund the continued development of the company’s recombinant botulinum (rBOT) and next-generation anthrax vaccine (NGAV) candidates.

Emergent BioSolutions initiates Phase II trial of oral typhoid vaccine candidate

by Ted Purlain on June 5, 2008

Abdun_nabi

Daniel J. Abdun-Nabi

ROCKVILLE, MD. —Emergent BioSolutions Inc. announced that dosing of patients has begun in a U.S. Phase II clinical trial of the company’s single-dose oral typhoid vaccine candidate.

More than 3 million doses of BioThrax delivered to HHS

by Ted Purlain on December 14, 2006

Biothrax

BioThrax

Emergent BioSolutions Inc. that it has successfully completed the fourth-quarter 2006 deliveries of more than 3 million doses of BioThrax (Anthrax Vaccine Adsorbed) to the Department of Health and Human Services.

Emergent BioSolutions’ typhoid vaccine achieves positive results in clinical study

by Ted Purlain on August 30, 2005

Typhoid_salmonella_

GAITHERSBURG, Md. — Emergent BioSolutions announced positive results from a Phase II clinical study evaluating a simplified dosing regimen for the company’s next-generation single-dose oral typhoid vaccine.